What condition is characterized by hamartomatous polyps throughout the GI tract and mucocutaneous hyperpigmentation?

Peutz-Jeghers syndrome is characterized by the presence of hamartomatous polyps throughout the gastrointestinal (GI) tract, as well as distinctive mucocutaneous hyperpigmentation, particularly around the lips, mouth, and on the palms and soles. These polyps can lead to various complications, including obstruction and an increased risk of certain types of cancer due to the syndrome's genetic basis.

The hyperpigmentation seen in Peutz-Jeghers syndrome is a key diagnostic feature that helps differentiate it from other conditions. The GI polyps typically have a characteristic arborizing pattern, and they tend to start developing in childhood or early adolescence, which is also a noteworthy aspect of the syndrome.

Other conditions listed do not share these specific features. For instance, dermatographia refers to a skin condition that results in raised welts after scratching, but it does not involve GI polyps or hyperpigmentation. Crohn's disease is an inflammatory bowel disease that can cause various lesions in the GI tract but is not associated with hamartomatous polyps or hyperpigmentation. Celiac disease involves an immune response to gluten and primarily affects the small intestine but does not present with the specific polyps or hyperpigmentation of Peutz