What is a symptom of hypothyroidism?

Myxedema with puffiness of the face is a classic symptom of hypothyroidism. This condition arises from the accumulation of mucopolysaccharides in the skin and other tissues due to a deficiency of thyroid hormones. In hypothyroidism, the metabolism slows down, leading to various physiological changes, including the retention of fluids in tissues, which manifests as puffiness in the face and other areas, such as the hands and feet. This clinical finding is often associated with more severe or longstanding cases of hypothyroidism and is part of a broader constellation of symptoms, including fatigue, cold intolerance, and dry skin.

In contrast, the other choices describe symptoms typically associated with hyperthyroidism or conditions unrelated to low thyroid hormone levels. Increased heart rate, weight loss, and excessive sweating are common in hyperthyroid states where the body's metabolism accelerates, leading to symptoms that are quite the opposite of what one would expect in hypothyroidism.