What is characteristic of fibrous dysplasia?

Fibrous dysplasia is characterized by the replacement of normal bone tissue with fibrous tissue, which can lead to the formation of lesions that are radiolucent on imaging studies. This change results in a bone that is weaker and more prone to deformity or fracture. The condition does not primarily involve inflammation or necrosis; rather, its hallmark is the abnormal accumulation of fibrous tissue within the bones, leading to a specific clinical and radiographic appearance.

The presence of scarring tissue substituting normal bone in fibrous dysplasia is what distinguishes it from other bone pathologies. The fibrous tissue may also contain immature bony trabecular elements, but it does not exhibit the characteristics of a true bone regenerate or mature bone structure. This unique presentation affects how the condition is diagnosed and managed, emphasizing the importance of recognizing the underlying histopathological changes.