What is the maximum dose of Prilocaine (Citanest) per kilogram?

Prilocaine, a local anesthetic commonly used in dental and medical procedures, has a maximum recommended dose of 7 mg/kg. This guideline is based on pharmacological research and clinical studies which have established that doses above this threshold can increase the risk of systemic toxic effects, particularly methemoglobinemia, which is a condition that reduces the ability of hemoglobin to carry oxygen. Ensuring that the dose remains within safe limits is crucial to prevent adverse reactions.

In clinical practice, clinicians refer to these maximum dose recommendations to safely manage local anesthetic administration, taking into consideration the individual patient’s weight and health status. Proper dosing not only improves the efficacy of the anesthesia but also minimizes potential complications.